Ingredient

Myo-Inositol

Amount per serving

212mg

% against RDA

-

Absorbability comments

The form most studied for menstrual health and PCOS.

Ingredient:

Amount per serving:

% against RDA:

Absorbability comments:

Myo-Inositol

212mg

-

The form most studied for menstrual health and PCOS.

Benefits

Inositol is a carbohydrate that plays a crucial role in cell signalling, lipid metabolism, and maintaining hormonal balance. Myo-Inositol is extensively studied for its ability to improve ovarian health, menstrual regularity, and insulin sensitivity, making it a key player in supporting metabolic health. Research has shown that Inositol is particularly effective in populations with PCOS (Polycystic Ovary Syndrome), where it aids in reducing androgen levels, improving ovulatory function, and restoring cycle regularity. Studies comparing Inositol with Metformin have revealed that Inositol, when used in combination with Metformin, improves outcomes such as ovulation rates and hormonal balance more effectively than Metformin alone. In certain cases, Inositol has even been just as effective as Metformin in improving insulin sensitivity and menstrual cycle length. Furthermore, regular supplementation with Inositol has demonstrated significant benefits in shortening cycle length and enhancing menstrual regularity in individuals experiencing irregular cycles, providing a safe and natural approach to hormonal health.

Evidence

  • Inositol is the best researched supplement for PCOS by improving hormone levels, menstrual irregularities, egg quality and hirsutism scores
  • A systematic review of randomized control trials in PCOS found that inositol supplementation led to spontaneous ovulation improvement in 65% of participants, compared to 50% in a group taking metformin

Unfer V, Nestler JE, Kamenov ZA, Prapas N, Facchinetti F. Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials. Int J Endocrinol. 2016;2016:1849162. doi: 10.1155/2016/1849162. Epub 2016 Oct 23. PMID: 27843451; PMCID: PMC509780 Unfer V, Nestler JE, Kamenov ZA, Prapas N, Facchinetti F. Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials. Int J Endocrinol. 2016;2016:1849162. doi: 10.1155/2016/1849162. Epub 2016 Oct 23. PMID: 27843451; PMCID: PMC5097808.